Von Willebrand disease

This disease occurs when the body lacks the von Willebrand factor (VWF), a substance that allows platelets to stick together and form clots. Most cases of von Willebrand are relatively mild, and people may only require treatment if they are injured or undergo surgery.

While many platelet disorders involve a reduction in the number of platelets present in the blood or their function, several conditions can cause an excess of platelets.

Signs of platelet and clotting disorders include:

  • difficulty forming blood clots at wounds or controlling bleeding
  • injuries that are slow to heal or keep re-opening
  • unexplainable bruising or skin that easily bruises
  • unexplainable bleeding from the nose, gums, gastrointestinal system, or urogenital system

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