Scleroderma is a condition that results in thickened areas of skin and sometimes problems with organs and blood vessels. Scleroderma is caused by the immune system attacking the tissue under the skin and around internal organs and blood vessels. This causes scarring and thickening of the tissue within these areas. There are several different types of scleroderma and some types are relatively mild and may eventually improve on their own, while others can lead to severe and life-threatening problems.
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